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Tumors metastatic to the orbit
C L Shields1, J A Shields, M Peggs
1Oncology Service, Wills Eye Hospital, Philadelphia, PA 19107.
Ophthalmic Plastic and Reconstructive Surgery
|January 1, 1988
Summary
Orbital metastasis most commonly originates from breast cancer. This review highlights key symptoms, diagnostic challenges, and poor prognosis for orbital tumors, especially from lung cancer.
Area of Science:
- Ophthalmology
- Oncology
Background:
- Orbital metastasis represents a significant oncological challenge.
- Understanding primary tumor origins and clinical presentation is crucial for patient management.
Purpose of the Study:
- To analyze the primary tumor sites, clinical features, and outcomes of orbital metastatic disease.
- To review the existing literature on orbital metastatic tumors.
Main Methods:
- Retrospective review of 35 consecutive cases with orbital metastasis.
- Analysis of presenting signs, symptoms, primary tumor origin, and patient survival.
Main Results:
- Breast cancer was the most common primary site (51%), followed by prostate (17%).
- Common symptoms included diplopia, proptosis, and palpable mass; 26% had no prior cancer history.
- Average survival was 13 months, with lung carcinoma metastasis showing the poorest prognosis (4 months).
Conclusions:
- Orbital metastasis is frequently secondary to breast cancer.
- Early detection and understanding of prognosis are vital for managing orbital metastatic disease.