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Frontal sinus mucopyocele in cystic fibrosis

M R Levine1, Y D Kim, W Witt

  • 1Division of Opthalmology, Mt. Sinai Medical Center, Cleveland, Ohio.

Insights

Cystic fibrosis patients with eye symptoms like proptosis or diplopia may have frontal sinus mucoceles. Surgical treatment, including osteoplastic flap and fat obliteration, proved successful for these cases.

Area of Science:

  • Otolaryngology
  • Ophthalmology
  • Genetics

Background:

  • Cystic fibrosis (CF) is a genetic disorder affecting multiple organs, including sinuses.
  • Frontal sinus mucoceles can cause significant ocular and neurological symptoms.
  • Early diagnosis and treatment are crucial for managing complications.

Observation:

  • Two patients with cystic fibrosis presented with symptoms suggestive of frontal sinus pathology.
  • An 18-year-old male reported a year of left eye proptosis.
  • A 28-year-old female experienced 3 months of intermittent diplopia.

Findings:

  • Computed tomographic (CT) scans confirmed frontal sinus mucoceles in both patients.
  • Both patients underwent successful surgical treatment using an osteoplastic flap with fat obliteration.
  • The surgical intervention resolved the presenting ocular symptoms.

Implications:

  • Suggests a link between cystic fibrosis and the development of frontal sinus mucoceles.
  • Highlights the importance of considering paranasal sinus mucoceles in CF patients with specific symptoms.
  • Emphasizes the efficacy of surgical management for these complex cases.

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