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Updated: Jan 19, 2026
10:17
High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
Published on: April 23, 2019
10.2K
Polydrug use - prevalence and registration.
Summary
Polydrug use is common, affecting 79% of patients. The study highlights underreporting of multiple substance dependence diagnoses, emphasizing the need for accurate classification for better overdose prediction and treatment.
Area of Science:
- Addiction medicine
- Psychiatry
- Public health
Background:
- Polydrug use is a significant factor in fatal overdoses and increased treatment needs.
- Understanding the prevalence of multiple substance dependence is crucial for effective intervention.
Purpose of the Study:
- To investigate the prevalence and registration accuracy of multiple substance dependence.
- To compare diagnostic rates using ICD-10 and ICD-11 criteria.
Main Methods:
- 147 inpatients at a hospital's addiction treatment department were assessed.
- Substance dependence diagnoses were registered and reassessed using ICD-10 (F19) and ICD-11 (6C4F) criteria.
Main Results:
- 79% of patients (116/147) were dependent on two or more substances.
- ICD-10 diagnosis F19 prevalence increased from 15% to 35% after reassessment.
- ICD-11 diagnosis 6C4F identified a 79% prevalence of multiple substance dependence.
Conclusions:
- There is significant underreporting of the ICD-10 diagnosis F19 for multiple substance dependence.
- Accurate diagnosis of polydrug use is vital for predicting overdose risk, prognosis, and tailoring treatment.
- ICD-11 criteria offer a more comprehensive assessment of multiple substance dependence.
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