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Mixed Acinar-Endocrine Carcinoma (MAEC) Arising in Duodenal Pancreatic Heterotopia
Phoenix D Bell1, Tom C DeRoche2, Aaron R Huber1
1Department of Pathology, University of Rochester Medical Center, Rochester, NY, USA.
Abstract:
Mixed acinar-endocrine carcinoma (MAEC) of the pancreas is a rare neoplasm, consisting of at least 25%-30% of acinar and neuroendocrine populations. Patients are often middle-aged and present with nonspecific symptoms. Imaging typically reveals a solid lesion in the pancreatic head. Management involves surgical resection and the overall prognosis is variable. Here, we present a case of a 48-year-old male who presented with a MAEC arising from duodenal pancreatic heterotopia. This is the one of the first cases, with histologic evidence, of MAEC arising from pancreatic heterotopia.
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