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Related Experiment Video

Updated: Jan 18, 2026

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy

A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy

Published on: November 3, 2016

Neonatal Functional Treatment for Pierre Robin Sequence.

Gabriella Galluccio¹, Valentina Mazzoli¹, Roberto Vernucci¹

¹Department of Orthodontics and Maxillofacial Surgery, Sapienza University of Rome School of Dentistry, Rome, Italy.

Turkish Journal of Orthodontics

|October 1, 2019

Summary

This summary is machine-generated.

This study shows that functional obturator plates significantly improve feeding and weight gain in infants with Pierre Robin Sequence (PRS). This orthodontic approach can reduce or eliminate the need for surgical intervention in many cases.

Keywords:

Pierre Robin Sequence cleft palate functional orthodontic treatment obturator plate

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Area of Science:

Craniofacial anomalies
Pediatric dentistry
Orthodontics

Background:

Pierre Robin Sequence (PRS) is a condition characterized by micrognathia, glossoptosis, and cleft palate, often causing airway obstruction.
Comprehensive care for PRS involves orthodontic management throughout a child's growth period.

Purpose of the Study:

To evaluate the effectiveness of a functional orthodontic approach in managing Pierre Robin Sequence.
To assess functional outcomes, treatment duration, and appliance usage in PRS patients.

Main Methods:

Retrospective analysis of PRS patients treated with a functional approach between 2013-2017.
Treatment involved early impression and plate supply, stimulated bottle feeding, and plate adjustments for palatal growth.

Main Results:

All patients demonstrated positive outcomes, including improved feeding and weight gain.
The treatment facilitated reaching the surgical phase without adverse effects.
The functional obturator plate supported mandibular growth and palate development.

Conclusions:

Functional obturator plates can reduce or eliminate the need for surgical intervention in PRS by addressing mandibular growth alterations.
Persistent nutritional issues may necessitate surgical approaches like mandibular osteodistraction.