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Updated: Jan 6, 2026

Lateral Root Inducible System in Arabidopsis and Maize
Published on: January 14, 2016
Noncanonical auxin signaling regulates cell division pattern during lateral root development
Rongfeng Huang1, Rui Zheng2,3, Jun He4
1Horticulture Biology and Metabolomics Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, 350002 Fuzhou, Fujian, China.
Plant organogenesis relies on cell division patterns. This study reveals that auxin activates Mitogen-Activated Protein Kinase (MAPK) signaling through transmembrane kinases (TMKs) to control cell division during lateral root development.
Area of Science:
- Plant biology
- Developmental biology
- Molecular signaling
Background:
- Organogenesis in plants and animals requires coordinated cellular processes.
- Cell division patterns are crucial for organ shape but are poorly understood.
- Auxin distribution is linked to plant organogenesis, including lateral root development, but its role in cell division regulation is unclear.
Purpose of the Study:
- To elucidate the mechanism by which auxin regulates cell division patterns during plant lateral root development.
- To identify the signaling pathways connecting auxin to cell division control.
Main Methods:
- Investigated the role of transmembrane kinases (TMKs) and Mitogen-Activated Protein Kinase (MAPK) pathways in auxin signaling.
- Utilized genetic analysis and biochemical assays to study protein interactions and phosphorylation.
- Examined the impact of TMK and MAPK pathway components on lateral root development.
Main Results:
- Auxin activates MAPK signaling through TMKs to control cell division patterns in lateral root development.
- TMK1/4 and MKK4/5-MPK3/6 pathways are essential for orienting cell divisions during lateral root formation.
- TMKs directly interact with and phosphorylate MKK4/5, mediating auxin's activation of the MKK4/5-MPK3/6 signaling cascade.
Conclusions:
- TMK-mediated noncanonical auxin signaling connects auxin and MAPK pathways.
- This signaling is crucial for regulating cell division patterns and is essential for plant development.
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