Perinatal Outcomes Following Assisted Reproductive Technology

Area of Science:

• Reproductive Medicine
• Perinatal Health
• Assisted Reproductive Technology

Background:

• Assisted reproductive technology (ART) is increasingly utilized, encompassing advanced applications like donor gametes, surrogacy, and preimplantation genetic testing (PGT).
• Evaluating the perinatal outcomes and long-term safety for both women and children is crucial with the widespread adoption of these technologies.

Purpose of the Study:

• To review and detail perinatal outcomes associated with routine and extended ART procedures.
• To focus specifically on singleton pregnancies undergoing ART.

Main Methods:

• Literature review of perinatal outcomes related to various ART procedures.
• Analysis focused on singleton pregnancies resulting from ART.

Main Results:

• Some ART procedures are associated with an increased risk of adverse perinatal outcomes.
• The absolute increase in risk for adverse perinatal outcomes remains generally low across studied ART applications.

Conclusions:

• Clinicians require comprehensive knowledge of ART-associated perinatal risks to effectively counsel and manage patients.
• While risks exist, the absolute increase in adverse perinatal outcomes for singleton pregnancies undergoing ART is modest.