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Pancreas divisum inversus.
Matteo Renzulli1, Nico Pagano2, Rita Golfieri1
1Radiology Unit, Department of Experimental, Diagnostic and Speciality Medicine, Sant'Orsola Hospital, University of Bologna, Bologna, Italy.
Clinical Anatomy (New York, N.Y.)
|October 3, 2019
Summary
This study investigated pancreatic duct variations using MRCP, finding normal variants in 97% of patients. A novel "pancreas divisum inversus" variant was identified, potentially improving diagnosis and understanding of pancreatic diseases.
Area of Science:
- Radiology and Imaging
- Anatomy
- Embryology
Background:
- Pancreatic duct variations are often incidental findings.
- Magnetic resonance cholangiopancreatography (MRCP) is the preferred imaging modality for the pancreatic ductal system.
- The frequency and embryologic basis of pancreatic variants require further investigation.
Purpose of the Study:
- To prospectively determine the frequency of pancreatic ductal variants.
- To explore potential embryologic explanations for observed variants.
- To identify and characterize novel pancreatic ductal anomalies.
Main Methods:
- Prospective collection of pancreatic ductal anatomies from 202 patients undergoing MRCP.
- Analysis of imaging data to identify and classify pancreatic ductal variants.
- Comparison of findings with established classifications of pancreatic anatomy.
Main Results:
- Normal pancreatic ductal variants were identified in 97% of cases (196/202).
- Pancreas divisum variants were found in 3% of cases (6/202).
- A novel variant, potentially termed "pancreas divisum inversus" with an "isolated duct of Santorini," was observed in a subset of type C variants.
Conclusions:
- Pancreatic ductal variants are common, with most patients exhibiting normal variations.
- The newly described "pancreas divisum inversus" variant expands the understanding of pancreatic anatomy.
- Accurate reporting of rare variants is crucial for avoiding misdiagnosis and improving patient management.
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