ANALGESIC EFFECT OF INTRAVENOUS ASCORBIC ACID VERSUS ACELCOFENAC POST-TRANSALVEOLAR EXTRACTION: A CASE-CONTROL STUDY

Area of Science:

• Oral and Maxillofacial Surgery
• Pharmacology
• Pain Management

Background:

• Post-surgical pain, swelling, and trismus are common after third molar extractions.
• Efficient pain management is crucial for optimal postsurgical care.

Purpose of the Study:

• To compare the efficacy of intravenous vitamin C (2g) versus aceclofenac (100mg) in managing pain, swelling, and trismus post-third molar surgery.

Main Methods:

• A randomized study involving 101 patients undergoing third molar extraction.
• Patients received either 2g IV vitamin C or 100mg aceclofenac.
• Pain intensity, facial swelling, and mouth opening were assessed up to 3 days post-surgery.

Main Results:

• Both IV vitamin C and aceclofenac demonstrated similar analgesic efficacy by day 3.
• No significant differences were observed in facial swelling or mouth opening between the groups.
• Intravenous vitamin C was well-tolerated for managing postoperative complications.

Conclusions:

• Intravenous vitamin C (2g) and aceclofenac (100mg) offer comparable outcomes for pain, swelling, and trismus after impacted third molar extraction.
• Both interventions are suitable for managing postoperative sequelae in dental surgery.