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Atypical Keratitis Caused by Rothia Dentocariosa
Blake Williams1, Mansab Jafri2, Safa Arfeen3
1Department of Ophthalmology and Visual Science, University of Chicago, Chicago, IL, USA.
Ocular Immunology and Inflammation
|October 4, 2019
Summary
Rothia dentocariosa can cause atypical keratitis, a rare eye infection. This case report details successful treatment using a combination of cefuroxime and penicillin for this challenging microbial keratitis.
Area of Science:
- Ophthalmology
- Microbiology
Background:
- Corneal ulcers can arise from diverse microbial pathogens.
- Rothia dentocariosa is a rare cause of infectious keratitis.
Observation:
- A 49-year-old woman presented with atypical keratitis characterized by a non-discrete corneal ulcer.
- Initial treatment with fluoroquinolones and steroids was ineffective, with the infiltrate worsening and developing a branching appearance.
Findings:
- Cultures identified Rothia dentocariosa as the causative agent.
- Treatment with intrastromal cefuroxime and topical penicillin G resulted in complete resolution over 8 weeks.
- Literature review revealed only one prior case of Rothia dentocariosa keratitis.
Implications:
- Rothia dentocariosa represents an uncommon but significant cause of microbial keratitis.
- Atypical presentations may necessitate prolonged and specific antimicrobial therapy.
- Combination antibiotic therapy, including cefuroxime and penicillin, can be effective for refractory cases.
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