Related Experiment Video

Updated: Jan 6, 2026

New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation
08:45

New Thrombectomy Technique for Total Portal Vein Thrombosis in Liver Transplantation

Published on: June 27, 2025

1.3K

Venous thromboembolism in childhood: where is Brazil after 20 years?

Tayana Teixeira Mello1, Jorge David Aivazoglou Carneiro2, Guilherme Arantes Mello3

  • 1Instituto de Hematologia, Hemostasia e Trombose (IHHT), Campinas, SP, Brazil.

Hematology, Transfusion and Cell Therapy
|October 5, 2019
PubMed

Insights

Pediatric venous thromboembolism (VTE) is a growing concern in critically ill children, necessitating targeted prevention and treatment protocols. A national registry in Brazil is crucial for data collection and improved care.

Area of Science:

  • Pediatric Medicine
  • Hematology
  • Critical Care

Background:

  • Venous thromboembolism (VTE) is increasingly recognized in critically ill children due to improved survival rates.
  • International studies highlight unique pediatric VTE epidemiology, clinical presentation, morbidity, and mortality.
  • A significant knowledge gap exists in Brazil regarding pediatric VTE.

Purpose of the Study:

  • To update the understanding of pediatric VTE, including epidemiology, clinical aspects, and therapeutic strategies.
  • To emphasize the need for specific prevention and treatment protocols for pediatric VTE.
  • To advocate for a national registry to inform public health policies and improve care networks in Brazil.

Main Methods:

  • This is a review article.
  • It synthesizes existing international epidemiological data on pediatric VTE.
  • It discusses clinical presentation, treatment, and prevention strategies.

Main Results:

  • Pediatric VTE presents unique characteristics and significant health impacts.
  • There is an urgent need for specialized protocols for pediatric thrombosis.
  • Establishing a national registry is vital for Brazil.

Conclusions:

  • Improved data collection through a national registry is essential for developing effective pediatric VTE management in Brazil.
  • Enhanced educational initiatives in Pediatric Hemostasis are critical.
  • Addressing pediatric VTE requires a coordinated national approach.

Keywords:
ChildrenEpidemiologyRisk factorsVenous thrombosis

More Related Videos

Breakfast Habits among Schoolchildren in the City of Uruguaiana, Brazil06:48

Breakfast Habits among Schoolchildren in the City of Uruguaiana, Brazil

Published on: July 29, 2020

5.0K
Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis06:45

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis

Published on: February 10, 2023

15.7K

Related Concept Videos

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
262
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
245
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
188
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
231
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
165
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
175