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Transfer learning of deep neural network representations for fMRI decoding.

Michele Svanera1, Mattia Savardi2, Sergio Benini2

  • 1Department of Information Engineering, University of Brescia, Italy; Institute of Neuroscience and Psychology, University of Glasgow, UK.

Journal of Neuroscience Methods
|October 5, 2019
PubMed
Summary
This summary is machine-generated.

This study introduces a novel method to decode brain activity from fMRI data by transferring deep learning features. This approach significantly improves decoding performance compared to using imaging data alone.

Keywords:
Brain decodingConvolutional Neural NetworkDeep learningMultiVoxel Pattern AnalysisTransfer learningfMRI

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Area of Science:

  • Neuroscience
  • Machine Learning
  • Computer Vision

Background:

  • Deep neural networks, particularly Convolutional Neural Networks (CNNs), excel at object classification but face challenges in brain imaging due to limited data.
  • Functional Magnetic Resonance Imaging (fMRI) data scarcity hinders direct application of CNNs for decoding subject states or perceptions.

Purpose of the Study:

  • To develop a robust method for transferring information from deep learning (DL) features to fMRI data for improved decoding.
  • To establish a multivariate link between fMRI data and the fully connected layer (fc7) of a CNN for enhanced analysis.

Main Methods:

  • Utilized Reduced Rank Regression with Ridge Regularisation to connect fMRI data with CNN's fc7 layer.
  • Applied object image classification using reconstructed fc7 features on two fMRI datasets (movie clips and static images).

Main Results:

  • Demonstrated significant reconstruction of fc7 features from fMRI data.
  • Achieved significant decoding performance using the reconstructed fc7 features.

Conclusions:

  • The proposed method enhances fMRI-based decoding by mapping functional data to CNN features.
  • Benefits include unsupervised extraction of stimuli representations and dimensionality reduction for high-dimensional neuroimaging data.