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Updated: Jan 6, 2026

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Published on: December 27, 2018
Enhanced three-photon activity triggered by the AIE behaviour of a novel terpyridine-based Zn(ii) complex bearing a
Zhihui Feng1, Dandan Li1, Mingzhu Zhang1
1Institutes of Physics Science and Information Technology , College of Chemistry and Chemical Engineering , Key Laboratory of Functional Inorganic Materials Chemistry of Anhui Province , Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized Materials , Anhui University , Hefei 230601 , People's Republic of China . Email: chemlidd@163.com ;
Abstract:
Multiphoton bioimaging benefits from good penetration of tissue, low phototoxicity and high resolution. Hence, development of efficient multiphoton imaging agents is highly desirable but remains challenging. Herein, a novel terpyridine-based Zn(ii) complex bearing a thiophene bridge was designed rationally and fabricated. Thanks to its aggregation-induced emission (AIE), DZ1 emitted bright yellow-green fluorescence (λ em = 575 nm) under physiological conditions. The three-photon spectral changes of DZ1 when binding with RNA unambiguously reflected its RNA-specific targeting behaviour, resulting in twofold enhancement in three-photon action cross-sections located at the second near-infrared window (1700 nm).
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