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Updated: Jan 6, 2026

Purification of H3 and H4 Histone Proteins and the Quantification of Acetylated Histone Marks in Cells and Brain Tissue
Published on: November 30, 2018
The posttranslational modification of HDAC4 in cell biology: Mechanisms and potential targets
Fei Hou1,2, Wei Wei1,2, Xiao Qin1,2
1Lupus Research Institute, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, China.
Abstract:
Histone deacetylase 4 (HDAC4) is a member of the HDACs family, its expression is closely related to the cell development. The cell is an independent living entity that undergoes proliferation, differentiation, senescence, apoptosis, and pathology, and each process has a strict and complex regulatory system. With deepening of its research, the expression of HDAC4 is critical in the life process. This review focuses on the posttranslational modification of HDAC4 in cell biology, providing an important target for future disease treatment.
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