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Updated: Jan 6, 2026

Development of New Therapeutic Applications Using Microfluidics
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Development of New Therapeutic Applications Using Microfluidics

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Emerging paper microfluidic devices.

Bingbing Gao1, Xin Li, Yaqiong Yang

  • 1School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing 211816, China. gaobb@ njtech.edu.cn bingfanghe@ njtech.edu.cn.

The Analyst
|October 8, 2019
PubMed
Summary
This summary is machine-generated.

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This review explores paper-based microfluidic devices, highlighting their fabrication, liquid manipulation, and applications in biochemical sensing. Paper

Area of Science:

  • Materials Science
  • Chemistry
  • Biology
  • Physics

Background:

  • Paper offers unique advantages like low cost, flexibility, and porosity.
  • Advancements in materials blur the lines between paper and other flexible membranes.
  • Paper's properties enable self-driven liquid pumping and integration into complex devices.

Purpose of the Study:

  • To review the development of microfluidic devices utilizing traditional paper and other flexible membranes.
  • To cover fabrication techniques, microfluidic manipulation, and sensing capabilities.
  • To explore the diverse applications of these paper-based systems.

Main Methods:

  • Review of existing literature on paper-based microfluidic devices.

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  • Analysis of fabrication methods for integrating paper into microfluidic systems.
  • Examination of sensing mechanisms and liquid manipulation techniques.

    • Main Results:

    • Paper can be considered a flexible membrane, and vice versa.
    • Paper-based devices are suitable for chromatographic analysis, electrochemical analysis, and wearable sensing.
    • These devices demonstrate effective manipulation of liquids and photoelectric responses.

    Conclusions:

    • The review consolidates recent progress in paper-based microfluidics.
    • Paper and flexible membranes are increasingly interchangeable in device design.
    • Paper-based microfluidic devices offer versatile platforms for various scientific applications.