Design and rationale of the North Indian ST-Segment Elevation Myocardial Infarction Registry: A prospective cohort
Sameer Arora1,2, Arman Qamar3, Puneet Gupta4
1Division of Cardiology, University of North Carolina, Chapel Hill, North Carolina.
Insights
This study examines ST-segment elevation myocardial infarction (STEMI) care in North India, focusing on underserved populations. Findings aim to improve treatment strategies and patient outcomes for heart attacks in the region.
Area of Science:
- Cardiology
- Public Health
- Epidemiology
Background:
- ST-segment elevation myocardial infarction (STEMI) poses significant mortality and morbidity risks globally.
- Limited contemporary data exists on STEMI care processes and outcomes in India, particularly for underserved populations.
- Tertiary medical centers in New Delhi serve a large, socioeconomically disadvantaged patient group from various Indian states lacking specialized cardiovascular care.
Purpose of the Study:
- To establish the North Indian ST-segment elevation myocardial infarction (NORIN STEMI) registry.
- To gain insights into contemporary risk factor profiles, treatment practices, and prognosis for STEMI patients in an underserved North Indian population.
- To identify opportunities for enhancing STEMI care outcomes in India.
Main Methods:
- Prospective cohort study design.
- Data collection from government-funded, low-cost tertiary medical centers in New Delhi, India.
- Institutional Review Board approval and informed consent obtained from all participants.
Main Results:
- The NORIN STEMI registry provides crucial data on STEMI management in a specific Indian demographic.
- Analysis of risk factors, treatment patterns, and patient prognosis is ongoing.
- Results will highlight challenges and successes in managing STEMI within resource-limited settings.
Conclusions:
- The NORIN STEMI registry is vital for understanding STEMI care in underserved North Indian populations.
- Findings are expected to inform evidence-based strategies for improving STEMI management and patient outcomes across India.
- This research addresses a critical gap in cardiovascular care data for a vulnerable patient group.
Abstract:
ST-segment elevation myocardial infarction (STEMI) is associated with increased mortality and morbidity. Although remarkable progress has been made in the management of STEMI in high-income countries, contemporary data to evaluate processes and outcomes of STEMI care in India is limited. The North Indian ST-segment elevation myocardial infarction (NORIN STEMI) registry is a prospective cohort study based at government funded and largely free of cost tertiary medical centers in New Delhi, India. These hospitals serve a large proportion of the patients with lower socioeconomic status presenting from multiple states in India, as many centers in these states lack adequate specialized cardiovascular care. The study has been approved by the Institutional Review Boards of each institution and informed consent has been obtained from study participants. The NORIN STEMI registry aims to provide important insights regarding contemporary risk factors profiles, practice patterns, and prognosis in patients with STEMI in an underserved population in North India. These findings may identify opportunities to improve the outcomes of patients with STEMI in India.
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