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Updated: Jan 6, 2026

Simultaneous Data Collection of fMRI and fNIRS Measurements Using a Whole-Head Optode Array and Short-Distance Channels
Published on: October 20, 2023
A dual-tuned 17 O/1 H head array for direct brain oximetry at 3 Tesla
Karthik Lakshmanan1,2, Seena Dehkharghani1, Guillaume Madelin1,2,3
1Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, New York.
Purpose:
To design and build a dual-tuned 17 O/1 H coil for direct brain oximetry at 3T.
Methods:
A dual-tuned 17 O/1 H coil comprising 2 degenerate mode birdcage coils was constructed to facilitate high-sensitivity 17 O and 1 H imaging. In vivo 17 O brain images were acquired in a healthy volunteer using a fermat looped orthogonally encoded trajectories sequence, together with high-resolution structural brain 1 H images.
Results:
Natural abundance 17 O images with a nominal resolution of 8 mm3 were acquired in under 20 minutes exhibiting clear delineation of the physiological 17 O distribution. One-millimeter isotropic 1 H structural brain images demonstrated excellent quality and anatomical detail using routine clinical imaging sequence parameters and parallel acceleration.
Conclusion:
A dual-tuned 17 O/1 H array was constructed to enable high-sensitivity 17 O and 1 H imaging under standard clinical 3 T scanning conditions.

