Related Experiment Video
Updated: Aug 13, 2026

Studying Cell Cycle-regulated Gene Expression by Two Complementary Cell Synchronization Protocols
Published on: June 6, 2017
Chalone-like inhibition of DNA synthesis in helminths
Abstract:
Chalone-like inhibitory activity was found in extracts from tissues of Taenia crassiceps cysticercus and tissues of adult Ascaris suum. The inhibitory effects were partially species nonspecific: The extracts from T. crassiceps larvae inhibit both T. crassiceps and Mesocestoides corti larvae DNA synthesis. Extracts from A. suum, however, inhibit only T. crassiceps. Besides them, the inhibitory factor from mouse brain inhibits both T. crassiceps and M. corti DNA synthesis. When the inhibitory factor from A. suum was applied 4 times during 24-hr culture (at 6-hr intervals), the inhibitory effect was decreased.
Related Concept Videos
Eukaryotic Transcription Inhibitors
Eukaryotic transcription inhibitors usually contain two distinct domains, a DNA...
Inhibitors of Bacterial Protein Synthesis
Inhibitors of Bacterial DNA Synthesis
Inhibitors of Viral Protein Synthesis
Antiviral Nucleoside Inhibitors
Anthelminthic Agents

