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HLA-B*15:47:01 allele with undefined serological equivalent considered as B Blank
Judith Desoutter1,2, Valentine Jacob1,2, Nicolas Guillaume1,2
1Department of Histocompatibility, Amiens University Medical Center, Amiens, France.
Abstract:
We report a discordance between complement-dependent cytotoxicity and next-generation sequencing molecular typing revealing HLA-B*15:47:01 allele with undefined serological equivalent confirmed by high-level immunization against the B15 serotype. Due to the high-level immunization against HLA-B15 and B70 antigens, we considered the HLA-B*15:47:01 allele to be B Blank and not as B15 or B70 serological specificity.
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