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Related Experiment Video

Updated: Jan 6, 2026

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Comorbidities in Patients with Psoriasis.

A Sultana1, S I Bhuiyan, M M Mahmud

  • 1Dr Abida Sultana, Associate Professor, Department of Dermatology and Venereology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.

Mymensingh Medical Journal : MMJ
|October 11, 2019
PubMed
Summary
This summary is machine-generated.

Psoriasis patients have significantly more comorbidities, including diabetes mellitus and hypertension, compared to healthy individuals. While the severity of these conditions was mild, understanding these patterns is crucial for comprehensive patient care.

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Area of Science:

  • Dermatology
  • Internal Medicine
  • Epidemiology

Background:

  • Psoriasis is a chronic inflammatory disease linked to numerous comorbidities.
  • Cardiovascular comorbidities are recognized, but many psoriasis-associated comorbidities remain understudied.
  • Identifying comorbidity patterns is essential for improving patient management.

Purpose of the Study:

  • To investigate and identify comorbid conditions in patients diagnosed with psoriasis.
  • To compare the prevalence of comorbidities in psoriasis patients versus a healthy control group.

Main Methods:

  • An observational case-control study involving 150 psoriasis patients and 150 age-matched healthy controls.
  • Data collection included physical examinations, structured questionnaires, and laboratory tests (blood sugar, creatinine, liver function tests).
  • Diagnostic tests included chest X-ray and abdominal ultrasound; Charlson-Age Comorbidity Index (CACI) was used to assess mortality risk.

Main Results:

  • The mean age of psoriasis patients was 38.64 years.
  • Top comorbidities in psoriasis patients were diabetes mellitus (4.67%), hypertension (4%), and ischemic heart disease (3.33%).
  • Psoriasis patients exhibited a significantly higher rate of comorbidities (single or multiple) compared to controls (p<0.05).

Conclusions:

  • Comorbidity occurrence is significantly higher in psoriasis patients than in the general population.
  • Despite mild severity, identified comorbidities necessitate focused patient care strategies.
  • The Charlson-Age Comorbidity Index indicated similar mortality risks between groups, warranting further investigation.