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Updated: Jan 6, 2026
09:29
Early Viral Entry Assays for the Identification and Evaluation of Antiviral Compounds
Published on: October 29, 2015
30.7K
[Antiviral therapy for general practitioners]
Aline Leuba1, Nicolas Lagnaux1, Alix Cinoa1
1Service de médecine interne générale, Centre hospitalier de Bienne, Chante-Merle 84, 2501 Bienne.
Revue Medicale Suisse
|October 11, 2019
Summary
Antiviral therapies and vaccines are crucial for managing common viral infections like influenza and hepatitis C. Recent advancements include new treatments for hepatitis C, influenza, and improved prophylaxis for cytomegalovirus (CMV) infections.
Area of Science:
- Virology
- Infectious Diseases
- Pharmacology
Background:
- Viral infections are widespread but often self-limiting, necessitating targeted antiviral therapies.
- Treatment options are currently available for specific viruses including Herpes Simplex Virus (HSV), Varicella-Zoster Virus (VZV), Cytomegalovirus (CMV), Influenza A and B, and Hepatitis B and C.
- Vaccination remains a primary strategy for preventing viral infections.
Purpose of the Study:
- To provide a comprehensive overview of current and emerging antiviral therapies.
- To highlight recent therapeutic advancements and ongoing developments in viral infection management.
Main Methods:
- Review of existing literature on antiviral treatments.
- Summary of recently approved and investigational antiviral drugs.
- Discussion of vaccination strategies for viral disease control.
Main Results:
- Hepatitis C virus (HCV) infections can now be treated with high success rates.
- Baloxavir has emerged as a new treatment option for influenza.
- Letermovir offers improved prophylaxis for Cytomegalovirus (CMV) in hematopoietic stem cell transplant recipients.
- A new vaccine for zoster is anticipated to become available.
Conclusions:
- Significant progress has been made in treating previously challenging viral infections like HCV.
- New therapeutic agents and vaccines are expanding the armamentarium against viral pathogens.
- Ongoing research and development promise further improvements in managing viral diseases.
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