Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Modeling and Similitude01:12

Modeling and Similitude

567
Scaled modeling is a fundamental technique in engineering, enabling the study of large and complex systems by creating smaller, manageable replicas that recreate critical characteristics of the original. In hydrology and civil infrastructure, for example, scaled models of dams help analyze water flow, turbulence, and pressure. This method allows for accurate predictions of real-world behavior within a controlled environment, significantly reducing the cost and time involved in full-scale...
567
Brick Sizes01:21

Brick Sizes

273
Brick sizing plays a crucial role in construction, influencing both the aesthetics and structural integrity of buildings. Bricks are defined by three dimensions: width, thickness, and length. They are commonly designed to fit modular measurements, typically in multiples of 4 inches or 8 inches in width, to facilitate uniform construction and compatibility with other building materials.
Modular bricks are the most common type and are sized to include the mortar joint, which is essential for...
273
Modeling in Therapy01:26

Modeling in Therapy

348
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
348
Steps in the Modeling Process01:14

Steps in the Modeling Process

586
Albert Bandura's theory of observational learning identifies four critical processes: attention, retention, motor reproduction, and reinforcement or motivation.
Attention is the first necessary component for observational learning. It involves focusing on what the model is doing and saying. For example, if you decide to take a drawing class to enhance your skills, you need to pay close attention to the instructor's words and hand movements. The characteristics of the model significantly...
586
Reinforced Brick Masonry01:15

Reinforced Brick Masonry

1.6K
Reinforced brick masonry is an advanced construction technique that enhances the structural integrity of brick walls by incorporating steel reinforcements. These reinforcements are either placed within the hollow cores of bricks or sandwiched between two layers of masonry, known as wythes, and are then secured in place with grout. Grout is a fluid mixture composed of Portland cement, aggregate, and water, providing the necessary bonding agent for the steel and brick.
To fortify brick walls...
1.6K
Brick Classifications01:16

Brick Classifications

331
Bricks, a fundamental component of construction, are categorized based on their application and structural characteristics into several types. These include facing bricks, building bricks, hollow bricks, paving bricks, and firebricks. Facing bricks, also referred to as face bricks, are primarily used for both structural support and visual appeal, making their appearance a crucial aspect. In contrast, building bricks are typically used in concealed sections of a structure, such as behind the...
331

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rules railroad: Syntax-inspired diagrams for visualizing and understanding rule-based model specifications.

PLoS computational biology·2026
Same author

CuiT is a Cu importer required for metal homeostasis in Salmonella enterica.

bioRxiv : the preprint server for biology·2026
Same author

Systems biology graphical notation: process description language level 1 version 2.1.

Journal of integrative bioinformatics·2026
Same author

Mathematical modeling reveals ferritin as the strongest cellular driver of dietary iron transfer block in enterocytes.

PLoS computational biology·2025
Same author

Verification and reproducible curation of the BioModels repository.

bioRxiv : the preprint server for biology·2025
Same author

Immune digital twins for complex human pathologies: applications, limitations, and challenges.

NPJ systems biology and applications·2024
Same journal

Modeling single nucleus microglia across species identifies immune pathways and therapeutic candidates in Alzheimer's disease.

NPJ systems biology and applications·2026
Same journal

Metabolic set theory: a generalized model of microbial interactions.

NPJ systems biology and applications·2026
Same journal

Gene prioritization across ancestries uncovers distinct molecular pathophysiology and therapeutic landscape in polycystic ovary syndrome.

NPJ systems biology and applications·2026
Same journal

A mathematical model of folate-mediated one-carbon metabolism in Down syndrome.

NPJ systems biology and applications·2026
Same journal

A minimal mechanically consistent model of smoothly dividing disk-shaped cells.

NPJ systems biology and applications·2026
Same journal

Virtual twins and the future of human developmental biology.

NPJ systems biology and applications·2026
See all related articles

Related Experiment Video

Updated: Jan 5, 2026

Interactive Molecular Model Assembly with 3D Printing
06:15

Interactive Molecular Model Assembly with 3D Printing

Published on: August 13, 2020

10.8K

ModelBricks-modules for reproducible modeling improving model annotation and provenance.

Ann E Cowan1,2, Pedro Mendes1,3,4, Michael L Blinov1,5

  • 11Center for Cell Analysis and Modeling, UConn Health, Farmington, CT USA.

NPJ Systems Biology and Applications
|October 12, 2019
PubMed
Summary
This summary is machine-generated.

Computational biology models are often single-use due to poor annotation. Introducing ModelBricks, small, annotated modules, enables reusable and understandable biological models through community contributions.

Keywords:
ComplexityComputer modellingModularitySoftware

More Related Videos

3D Printing of Biomolecular Models for Research and Pedagogy
09:17

3D Printing of Biomolecular Models for Research and Pedagogy

Published on: March 13, 2017

24.9K
Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury
07:06

Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury

Published on: March 21, 2025

1.0K

Related Experiment Videos

Last Updated: Jan 5, 2026

Interactive Molecular Model Assembly with 3D Printing
06:15

Interactive Molecular Model Assembly with 3D Printing

Published on: August 13, 2020

10.8K
3D Printing of Biomolecular Models for Research and Pedagogy
09:17

3D Printing of Biomolecular Models for Research and Pedagogy

Published on: March 13, 2017

24.9K
Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury
07:06

Block Building Task Identifies Distinct Groups of Left/Right-hand Choice Patterns After Unilateral Peripheral Nerve Injury

Published on: March 21, 2025

1.0K

Area of Science:

  • Computational Biology
  • Systems Biology
  • Bioinformatics

Background:

  • Current biological models lack standardized annotations, hindering reusability and understanding.
  • Recreating existing models or expanding them for new research is time-consuming and inefficient.

Purpose of the Study:

  • To propose a novel concept for creating annotated, reusable computational biology models.
  • To introduce 'ModelBricks' as modular, well-annotated components for building complex models.

Main Methods:

  • Developing a framework for small, annotated modules (ModelBricks) using standard languages like SBML.
  • Creating an open database for curated ModelBricks with unique identifiers and associated parameters.
  • Designing ModelBricks to be flexible, encapsulating various biological mechanisms.

Main Results:

  • ModelBricks facilitate the construction of new models that inherit annotations and provenance.
  • This approach simplifies model understanding, reuse, and expansion.
  • A flexible structure allows ModelBricks to represent diverse biological processes.

Conclusions:

  • ModelBricks offer a solution to the reusability problem in computational biology.
  • A community-driven database of ModelBricks will accelerate biological model development.
  • Standardized, annotated modules enhance model transparency and facilitate scientific collaboration.