Related Experiment Video
Updated: Jul 26, 2026
13:16
Assessment of DNA Contamination in RNA Samples Based on Ribosomal DNA
Published on: January 22, 2018
22.2K
Database resources of the National Center for Biotechnology Information
Eric W Sayers1, Jeff Beck1, J Rodney Brister1
1National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA.
Nucleic Acids Research
|October 12, 2019
Summary
The National Center for Biotechnology Information (NCBI) offers extensive biological data resources, including GenBank and PubMed. Recent updates enhance access to genetic information and sequence analysis tools.
Area of Science:
- Biotechnology
- Bioinformatics
- Genomic Data Management
Background:
- The National Center for Biotechnology Information (NCBI) is a vital resource for biological data.
- It hosts major databases like GenBank and PubMed, crucial for life science research.
- The Entrez system facilitates data retrieval across numerous specialized databases.
Purpose of the Study:
- To provide an overview of the NCBI's comprehensive online resources for biological information and data.
- To highlight recent advancements and updates to NCBI's platforms and databases.
- To inform users about the accessibility of these resources via the NCBI homepage.
Main Methods:
- Utilizing the Entrez system for search and retrieval across 35 distinct databases.
- Employing custom BLAST program implementations for sequence-based searching.
- Leveraging E-utilities as the programming interface for the Entrez system.
Main Results:
- NCBI offers extensive resources including GenBank, PubMed, and Entrez.
- New resources include an updated PubMed interface, sequence database search, and gene orthologs page.
- Numerous other resources like PMC, RefSeq, and various BLAST tools have been updated.
Conclusions:
- NCBI continuously enhances its suite of online tools and databases.
- These resources are essential for biological research, data analysis, and information retrieval.
- All updated resources are readily accessible through the main NCBI website.
Related Concept Videos
01:59Plant Breeding and Biotechnology
Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
02:26Protein Networks
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
02:55Synthetic Biology
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
Golden rice
Golden rice is a genetically modified...
02:26Protein Networks
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
01:30Health Information Technology and Healthcare Information System
Health Information Technology (HIT)
Health Information Technology, commonly called HIT, integrates advanced information systems and technology in healthcare settings. Its primary functions include:
Health Information Technology, commonly called HIT, integrates advanced information systems and technology in healthcare settings. Its primary functions include:
01:12Statistical Software for Data Analysis and Clinical Trials
Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...