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Nephrotoxin Microinjection in Zebrafish to Model Acute Kidney Injury
Published on: July 17, 2016
Acute kidney injury in acute Q fever
Adam G Stewart1, Jennifer Broom1, David Sowden1
1Department of Infectious Diseases, Sunshine Coast University Hospital, Sunshine Coast, Queensland, Australia.
Abstract:
Coxiella burnetii infection is not known to involve directly the kidneys. Kidney injury associated with Q fever usually manifests in the setting of chronic infection or endocarditis with development of immune complex deposition. Acute kidney injury (AKI) in the context of acute Q fever infection may be more pathologically heterogeneous. We describe two cases of severe AKI secondary to acute Q fever infection, each with marked differences in pathological characteristics, and clinical course.
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