Related Experiment Video
Updated: Jan 5, 2026

Taste Exam: A Brief and Validated Test
Published on: August 17, 2018
[Correlation study on Tibetan medicine Pterocephalus hookeri of bitter taste receptors based on molecular docking
Xuan-Hao Li1, Jin-Song Su1, Xiu-Hua Liu1
1Chengdu University of Traditional Chinese Medicine Chengdu 611137,China.
Abstract:
In order to study the interaction between Pterocephalus hookeri and bitter taste receptors,three-dimensional structural models of bitter taste receptors TAS2 R16,TAS2 R14 and TAS2 R13 were established by homology modeling in this paper. Maestro software was used for docking the chemical constituents of P. hookeri with bitter taste receptors. The results showed that 25 chemical components of P. hookeri can regulate three bitter taste receptors. And these components were mainly iridoid glycosides and phenolic acids.This research focused on the comprehensive application of homology modeling and molecular docking technology to explore the interaction between bitter chemical constituents of P. hookeri and bitter taste receptors. This study provided assistance in revealing pharmacodynamic basis of bitter Tibetan medicine at molecular level. It also provided new ideas and methods for the study of Tibetan medicine.
More Related Videos
07:50Author Spotlight: Integrating 2D-HPLC-MS and Molecular Networking in Natural Medicine Analysis
Published on: December 8, 2023
09:12Optimization of Processing of Tiebangchui with Highland Barley Wine Based on the Box-Behnken Design Combined with the Entropy Method
Published on: May 19, 2023
Related Concept Videos
The Physiology of Taste
Taste Buds and Receptors
Gustation
The Tongue and Taste Buds