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Risk factors in children with febrile seizures and their iron status

Banan Wadi Ahmed1, Basil Metti Hanoudi2, Basma Adel Ibrahim2

  • 1Central Child Teaching Hospital.

JPMA. the Journal of the Pakistan Medical Association
|October 12, 2019
PubMed

Insights

Iron deficiency significantly increases the risk of febrile seizures in children. This study found lower iron levels and higher rates of iron deficiency anemia in children experiencing febrile convulsions, highlighting iron status as a critical risk factor.

Area of Science:

  • Pediatrics
  • Hematology
  • Neurology

Background:

  • Febrile convulsions are common in young children.
  • Iron deficiency is a prevalent nutritional deficiency globally.
  • The relationship between iron status and febrile seizures requires further investigation.

Purpose of the Study:

  • To identify risk factors for febrile convulsions in children.
  • To evaluate the iron status of children with febrile convulsions.
  • To determine the association between iron deficiency and febrile seizures.

Main Methods:

  • A case-control study involving 80 febrile children aged 6-72 months.
  • Cases presented with fever and convulsions; controls had fever only.
  • Blood samples were analyzed for complete blood count, iron profile (serum ferritin, serum iron, total iron binding capacity).

Main Results:

  • Children with febrile convulsions were significantly younger.
  • The case group exhibited lower hemoglobin, packed cell volume, serum iron, and serum ferritin levels.
  • Iron deficiency anemia was more prevalent in cases (73.9%) than controls (26.1%).

Conclusions:

  • Iron deficiency is a significant risk factor for febrile seizures in children.
  • Children with febrile convulsions have poorer iron status.
  • Addressing iron deficiency may help mitigate the risk of febrile seizures.
Abstract

Keywords:
Febrile convulsionIron deficiency anaemiaRisk factors.

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