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COGNITIVE FUNCTIONS IN CHILDREN WITH TYPE I DIABETES

Basma Adel Ibrahim1, Sawsan Ali Hussein1, Wasnaa Hadi Abdullah1

  • 1AL-MUSTANSIRIYAH UNIVERSITY, BAGHDAD, IRAQ.

Wiadomosci Lekarskie (Warsaw, Poland : 1960)
|June 16, 2023
PubMed

Insights

Children with type 1 diabetes show impaired cognitive function and psychosocial difficulties compared to healthy peers. Poor glycemic control, including hyperglycemia and hypoglycemia, significantly impacts their cognition and mental health.

Area of Science:

  • Pediatric Endocrinology
  • Neuroscience
  • Clinical Psychology

Background:

  • Type 1 diabetes (T1D) is a chronic condition affecting children worldwide.
  • Cognitive function and psychosocial well-being are crucial for development and quality of life.
  • Understanding the impact of T1D on these domains is essential for comprehensive care.

Purpose of the Study:

  • To evaluate cognitive impairment patterns and severity in children with T1D.
  • To investigate the association between cognitive function and disease characteristics like onset and glycemic control.
  • To assess psychosocial functioning in children with T1D.

Main Methods:

  • A case-control study involving 60 children with T1D and 60 age-matched controls.
  • Cognitive function assessed using the Modified Mini-Mental State (MMMSE) examination.
  • Psychosocial functioning screened using the Pediatric Symptoms Checklist (PSC).
  • Analysis correlated cognitive and psychosocial scores with age, gender, socioeconomic status, disease onset, duration, HbA1c, and history of ketoacidosis/hypoglycemia.

Main Results:

  • Children with T1D had significantly lower M স্মৃতি (MMMSE) scores compared to controls (25.12±4.58 vs. 30.08±2.95).
  • Patients with T1D exhibited significantly lower PSC scores, indicating poorer psychosocial functioning (39.08±8.18 vs. 54.42±6.0).
  • Both hyper- and hypoglycemia were associated with impaired cognition and mental health.

Conclusions:

  • Children with T1D experience neurocognitive impairment compared to their non-diabetic peers.
  • Poor glycemic control, encompassing both hyperglycemia and hypoglycemia, negatively affects cognitive function and mental health in diabetic children.
  • Early detection and management of cognitive and psychosocial issues are vital for children with T1D.
Abstract

Keywords:
neuronal changesCognitionDiabetes mellituspsychological score

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