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Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
Published on: July 17, 2020
Accessing 1,2-Substituted Cyclobutanes through 1,2-Azaborine Photoisomerization
Zachary X Giustra1, Xinyu Yang1, Min Chen1
1Department of Chemistry, Boston College, Chestnut Hill, MA, 02467-3860, USA.
Abstract:
We provide a seminal example of the utility of the 1,2-azaborine motif as a 4C+1N+1B synthon in organic synthesis. Specifically, conditions for the practically scalable photoisomerization of 1,2-azaborine in a flow reactor are reported that furnish aminoborylated cyclobutane derivatives. The C-B bonds could also be functionalized to furnish a diverse set of highly substituted cyclobutanes.
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