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Updated: Mar 13, 2026

The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphosPh Complexes
Published on: April 10, 2015
Synthesis and Characterization of an N-Trifluoromethyl 1,4-Azaborine-Based Phosphine Ligand and Its Transition Metal
Maxwell Eaton1, Tomoya Ozaki1, Bo Li1
1Department of Chemistry, Boston College, Chestnut Hill, Massachusetts 02467-3860, United States.
Abstract:
The synthesis of N-trifluoromethyl 1,4-azaborine-based phosphine ligands (FinnPhos) is described. X-ray diffraction analysis of FinnPhos L1-CF3 and its N-methyl analogue reveals a stronger contribution of the neutral resonance form to the structure of the 1,4-azaborine ring. Density functional theory (DFT) calculations predict the FinnPhos to exhibit a unique η3-C,C,B coordination mode to Pd(0). We demonstrate that the N-trifluoromethyl ligand provides superior reactivity to its N-methyl and carbonaceous analogues in the Au-catalyzed cycloisomerization of 1,6-enynes.
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