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A Soluble Tetrazolium-Based Reduction Assay to Evaluate the Effect of Antibodies on Candida tropicalis Biofilms
Published on: September 16, 2022
Are reduced concentrations of chlorine-based disinfectants effective against Candida auris?
Jessica A Kumar1, Jennifer L Cadnum2, Annette L Jencson2
1Geriatric Research, Education, and Clinical Center, Louis Stokes Cleveland VA Medical Center, Cleveland, OH.
Abstract:
Chlorine-based disinfectants are commonly used in rooms of patients with Candida auris, but there is uncertainty regarding optimal concentrations that provide efficacy while minimizing the potential for adverse effects. We found that 2 chlorine-based disinfectants were effective against C auris with 1 minute of contact time at concentrations of 4,000 parts per million or higher. Lower concentrations were effective only with increased contact times that may not be practical in real-world health care settings.
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