The ESC-EORP Chronic Ischaemic Cardiovascular Disease Long Term (CICD LT) registry
Michel Komajda1, Francesco Cosentino2, Roberto Ferrari3,4
1Department of Cardiology, Saint Joseph Hospital, Paris, France.
Insights
The Chronic Ischaemic Cardiovascular Disease Long Term (CICD LT) registry tracked high-risk patients to evaluate adherence to treatment guidelines and long-term outcomes. This study offers insights into contemporary patient care and management strategies for CICD.
Area of Science:
- Cardiology
- Clinical Research
- Epidemiology
Background:
- The European Society of Cardiology (ESC) EURObservational Research Programme (EORP) established the Chronic Ischaemic Cardiovascular Disease Long Term (CICD LT) registry.
- Chronic Ischaemic Cardiovascular Disease (CICD) affects a significant population at high cardiovascular (CV) risk.
- Current treatment and outcomes for CICD patients require contemporary evaluation.
Purpose of the Study:
- To analyze the clinical profile, treatment modalities, and outcomes of patients with CICD.
- To assess adherence to ESC guidelines for prevention and stable coronary disease management in high-CV-risk patients.
- To determine mid- and long-term outcomes and their influencing factors in the CICD population.
Main Methods:
- Enrollment of 9,174 adult patients with documented CICD between May 2015 and July 2018 across 154 centers in 20 ESC countries.
- Collection of individual patient data on clinical profile, biology, and treatment.
- Scheduled two-year follow-up to assess clinical outcomes including mortality, hospitalizations, medication changes, and quality of life (EuroQol5D-5L).
Main Results:
- Data collection completed for a large cohort of CICD patients.
- Follow-up data on mortality, hospitalizations, and quality of life are being collected.
- Analysis will reveal adherence to guidelines and identify determinants of outcomes.
Conclusions:
- The CICD LT registry provides a comprehensive overview of contemporary care and outcomes for hospitalized CICD patients.
- Findings will offer valuable insights into the management of this prevalent cardiovascular disease.
- The study will highlight areas for improvement in guideline adherence and patient management.
Aims:
The European Society of Cardiology (ESC) EURObservational Research Programme (EORP) Chronic Ischaemic Cardiovascular Disease Long Term (CICD LT) registry aims to study the clinical profile, treatment modalities, and outcomes of patients diagnosed with CICD in a contemporary environment in order to assess whether these patients at high cardiovascular (CV) risk are treated according to ESC guidelines on prevention or on stable coronary disease and to determine mid- and long-term outcomes and their determinants in this population.
Methods And Results:
Nine thousand one hundred and seventy-four patients over 18 years with documented CICD defined by a history acute coronary syndrome with/without ST elevation, previous coronary revascularization, or stable coronary artery disease were enrolled between 1 May 2015 and 31 July 2018. Individual patient data on clinical profile, biology, and treatment modalities were collected across 154 centres from 20 ESC countries. Two years of follow-up is scheduled in order to determine the following clinical outcomes: all-cause and CV death, all-cause and CV hospitalizations, changes in medications, and quality of life using the EuroQol5D-5L score.
Conclusion:
The CICD LT is an international registry of care and outcomes of patients hospitalized with CICD which will provide insights into the contemporary profile and management of patients with this common disease.
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