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Mechano-chromic protein-polymer hybrid hydrogel to visualize mechanical strain
Masumi Taki1, Tadahiro Yamashita, Kazuki Yatabe
1Laboratory of Applied Mechanobiology, Department of Health Sciences and Technology, ETH Zürich, Vladimir-Prelog-Weg 4, 8093 Zürich, Switzerland. viola.vogel@hest.ethz.ch.
Soft Matter
|October 15, 2019
Abstract:
In a proof-of-concept study, a mechano-chromic hydrogel was synthesized here, via chemoenzymatic click conjugation of fluorophore-labeled fibronectin into a synthetic hydrogel co-polymers (i.e., poly-N-isopropylacrylamide/polyethylene glycol). The optical FRET response could be tuned by macroscopic stretch.
