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Smartphones as mobile microbiological laboratories.

D S Y Ong1, M Poljak2

  • 1Department of Medical Microbiology and Infection Control, Franciscus Gasthuis & Vlietland, Rotterdam, the Netherlands; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
|October 15, 2019
PubMed
Summary

Smartphones are transforming microbiology diagnostics by enabling portable, point-of-care (POC) testing. Further development of these mobile microbiological laboratories promises wider accessibility for infectious disease detection.

Keywords:
DiagnosticsInfectionMedical technologyMobilePoint-of-care testingSmartphone

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Area of Science:

  • Microbiology
  • Mobile Health (mHealth)
  • Diagnostic Technology

Background:

  • Point-of-care (POC) diagnostics offer advantages over traditional lab tests, including speed and portability.
  • Smartphones, with their advanced features, are increasingly integrated into POC platforms.
  • The widespread adoption of smartphones presents a significant opportunity for mobile health solutions.

Purpose of the Study:

  • To review the current advancements in utilizing smartphones as part of mobile microbiological laboratories.
  • To summarize the state-of-the-art in smartphone-based microbiological testing.

Main Methods:

  • A systematic review of peer-reviewed publications.
  • Literature search focused on smartphone-based microbiological testing.
  • Analysis of studies published between January 2015 and August 2019.

Main Results:

  • Smartphones serve multiple roles in POC testing: interfaces, microscopes, readers, and integrated platforms with methods like loop-mediated isothermal amplification (LAMP).
  • Smartphone-based tests are suitable for diverse settings, from remote to resource-rich areas.
  • Connectivity enables epidemiological surveillance and disease mapping.

Conclusions:

  • Smartphone-based POC tests for infectious diseases show promising results in proof-of-concept studies.
  • Further validation and improvement are needed for widespread clinical adoption.
  • Advancements are paving the way for large-scale implementation of mobile microbiological labs.