Related Experiment Video
Updated: Jan 5, 2026

Experimental Metastasis Assay
Published on: August 24, 2010
Cutaneous metastases as a presenting sign of metastatic NSCLC
William T McSweeney1, Kimberley Tan1
1Department of General Surgery, Caboolture Hospital, Caboolture 4510, Australia.
Abstract:
Cutaneous metastases are rare and often late signs of an internal malignancy; however, this can be the presenting sign in very rare cases. These typically have a characteristic appearance and distribution based on the underlying malignancy but can be difficult to distinguish from other malignant or benign dermatoses. We report a case of a 69-year-old female who presented for elective excision of two cutaneous, fast-growing lesions on the chest wall. The patient's past medical history is significant for a 45-pack-year smoking history. Pre-operative chest radiograph revealed a right upper lobe mass, with the lesions ultimately representing cutaneous metastases of a non-small-cell lung cancer. Although cutaneous metastases have been reported, difficulty remains in distinguishing other causes of cutaneous lesions from cutaneous metastases in the predominantly asymptomatic patient.
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