APOE ε4 is associated with younger age at ischemic stroke onset but not with stroke outcome

Cecilia Lagging¹, Erik Lorentzen², Tara M Stanne²+13

• ¹From the Department of Laboratory Medicine (C.L., T.M.S., A.P., C.J.), Institute of Biomedicine, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Clinical Genetics and Genomics (C.L., A.P., C.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Bioinformatics Core Facility (E.L.), University of Gothenburg, Sweden; Department of Clinical Sciences Lund (M.S., A.L.), Neurology, Lund University, Sweden; Department of Neurology and Rehabilitation Medicine (M.S.), Neurology, Skåne University Hospital, Malmö, Sweden; Department of Neurology (J.W.C.), Baltimore VA Medical Center and University of Maryland School of Medicine, Baltimore, MD; Department of Neurology (K.J.), Sahlgrenska University Hospital, Gothenburg, Sweden; Department of Clinical Neuroscience (K.J.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy University of Gothenburg, Sweden; Neurosciences (R.L.), Experimental Neurology, KU Leuven-University of Leuven; VIB-Center for Brain & Disease Research (R.L.); Department of Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (C.-L.P.), Washington University School of Medicine in St. Louis; J. Philip Kistler Stroke Research Center (N.S.R.), Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston; Stroke Division (V.T.), Florey Institute of Neuroscience and Mental Health, University of Melbourne, Heidelberg, Victoria, Australia; Department of Neurology (V.T.), Austin Health, Heidelberg, Victoria, Australia; Department of Neurology and Rehabilitation (D.W.), University of Cincinnati College of Medicine, OH; Faculty of Health (J.M.M.), University of Technology Sydney, Sydney, Australia; Hunter Medical Research Centre (J.M.M.), Newcastle, Australia; and Department of Neurology and Rehabilitation Medicine (A.L.), Neurology, Skåne University Hospital, Lund, Sweden. cecilia.lagging@gu.se.+1