Improved cellular bioactivity by heparin immobilization on polycarbonate film via an aminolysis modification for potential tendon repair
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Updated: Jan 5, 2026
Polyelectrolyte Complex for Heparin Binding Domain Osteogenic Growth Factor Delivery
Published on: August 22, 2016
Jingshu Guo1, Ke Li1, Congqin Ning2
1State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing 100049, China.
Abstract:
Tendon repair was an important part during tendon to bone healing. In the present study, heparin molecules were immobilized on the aminolyzed PCL surface to improve the cellular bioactivity for potential tendon repair. The effects of heparin immobilization on protein adsorption behavior and cellular bioactivity of NIH3T3 and ATDC5 cells were investigated. The results were shown as follows.
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