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Complete Genome Sequence of Citrobacter freundii Myophage Maleficent

Hayden H Wright1, Victoria Berkowitz1, Chandler O'Leary1

  • 1Center for Phage Technology, Texas A&M University, College Station, Texas, USA.

Microbiology Resource Announcements
|October 19, 2019
PubMed

Insights

Researchers sequenced the genome of Maleficent, a T4-like myophage. This bacteriophage infects Citrobacter freundii, a bacterium causing opportunistic infections in vulnerable populations.

Area of Science:

  • Microbiology
  • Virology
  • Genomics

Background:

  • Citrobacter freundii is an opportunistic pathogen within the Enterobacteriaceae family.
  • This bacterium poses risks to neonates and immunocompromised individuals.

Purpose of the Study:

  • To sequence the complete genome of the T4-like myophage, Maleficent.
  • To characterize a novel bacteriophage infecting Citrobacter freundii.

Main Methods:

  • Whole-genome sequencing of the Maleficent myophage.
  • Bioinformatic analysis of the viral genome.

Main Results:

  • The complete genome sequence of the Maleficent myophage was determined.
  • The phage was identified as a T4-like myophage.

Conclusions:

  • The genome sequence provides a foundation for understanding Maleficent's biology.
  • This research contributes to the study of bacteriophages targeting Citrobacter freundii.

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