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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
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Multiple atypical thymic carcinoids with paraneoplastic giant cell arteritis
Takashi Nakayama1, Sayaka Katagiri2, Takuma Kikkawa2
1Department of General Thoracic Surgery, Tokyo Metropolitan Tama Medical Center, 2-8-29 Musashidai, Fuchu, Tokyo, 183-8524, Japan. nakayama-takashi-0901@hotmail.co.jp.
General Thoracic and Cardiovascular Surgery
|October 19, 2019
Summary
Multiple atypical thymic carcinoids co-occurred with asymptomatic giant cell arteritis (GCA), a rare paraneoplastic disease. Complete tumor resection managed both conditions, showing decreased arteritis activity.
Area of Science:
- Oncology
- Rheumatology
- Pathology
Background:
- Multiple thymic carcinoids are rare neoplasms.
- Giant cell arteritis (GCA) is an uncommon paraneoplastic disease.
- The co-occurrence of thymic carcinoids and GCA is exceptionally rare.
Observation:
- A case of multiple atypical thymic carcinoids with intrathymic metastasis and asymptomatic paraneoplastic GCA is presented.
- Histopathological diagnosis confirmed atypical thymic carcinoids.
- The patient underwent complete tumor resection, followed by observation for GCA.
Findings:
- Positron emission tomography indicated reduced F-fludeoxyglucose uptake in systemic arteries post-resection, confirming paraneoplastic GCA.
- Thymic carcinoids can rarely present with intrathymic metastasis and induce paraneoplastic GCA.
- Complete tumor resection emerged as the optimal management strategy.
Implications:
- This case highlights the importance of considering GCA in patients with thymic carcinoids.
- Complete surgical resection of thymic carcinoids may effectively manage associated paraneoplastic GCA.
- Further research into the mechanisms linking thymic carcinoids and paraneoplastic syndromes is warranted.
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