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Updated: Jan 5, 2026
A Swin Transformer-Based Model for Thyroid Nodule Detection in Ultrasound Images
Published on: April 21, 2023
Night Shift Working Is Associated With an Increased Risk of Thyroid Nodules
Stefano Rizza1, Anna Neri, Alessandra Capanna
1Department of Systems Medicine (Dr Rizza, Dr Federici); Department of Biomedicine and Prevention (Dr Neri, Dr Capanna, Dr Grecuccio, Dr Pietroiusti, Dr Magrini, Dr Coppeta), University of Rome Tor Vergata, Rome, Italy.
Objectives:
To study thyroid alterations in health care workers according to their working status.
Methods:
We performed a retrospective study including 299 hospital employers who underwent in 2016 a periodic health surveillance checks in the Service of Occupational Medicine. According to the working status (rotating night-shift working [no. 160] vs day-working [no. 139]), we divided participant's clinical, anthropometric, and thyroid echographic characteristics.
Results:
Respect to day workers, rotating night-shift workers were slightly older and more frequently male whereas had similar thyroid stimulating hormone, Ft3, Ft4 levels, and autoimmunity (anti-TPO levels more than 30). Univariate and multivariate regression analysis revealed that rotating night shift work is associated to a significantly increased number of thyroid nodules.
Conclusions:
This retrospective report suggests that the alteration in the molecular clocks typical of rotating night-shift workers harbors a higher risk of thyroid nodule development compared with diurnal workers. This novel result deserves replication in larger cohorts since thyroid nodules not rarely can represent thyroid cancers.
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