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Updated: Jan 5, 2026
08:49
A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
16.4K
[Congenital giant melanocytic nevi]
G N Chistyakova1, A A Grishkina1, A V Kayumova1
1Urals Research Institute for Maternal and Child Care, Ministry of Health of Russia, Yekaterinburg, Russia.
Arkhiv Patologii
|October 19, 2019
Summary
This study reports a rare newborn tumor affecting the skin, brain, and liver. Researchers detail the unique morphological and immunohistochemical features of a giant tumor in the infant
Area of Science:
- Oncology
- Dermatology
- Pediatric Pathology
Background:
- Rare tumor diseases in newborns present diagnostic challenges.
- Massive tumor involvement requires comprehensive characterization.
Observation:
- A newborn infant presented with extensive skin, brain, and liver tumor involvement.
- The primary site of massive tumor growth was identified in the occipital head skin.
Findings:
- Morphological and immunohistochemical analysis revealed a giant tumor cell nidus.
- Characterization focused on the unique cellular and structural properties of the occipital tumor.
Implications:
- Understanding rare neonatal tumors aids in early diagnosis and treatment.
- Detailed characterization of such tumors contributes to the broader knowledge of pediatric oncology.
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