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Updated: Jan 5, 2026

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
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Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis

Published on: June 3, 2016

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[Adipocytic apoptosis and progressive obesity in children]

U S Oorzhak1, T Y Taranushenko1, А В Salmina1

  • 1Krasnoyarsk State Medical Academy.

Problemy Endokrinologii
|October 20, 2019
PubMed

Insights

Obesity is a growing global epidemic affecting all ages, leading to serious health issues and reduced life expectancy. Urgent public health strategies are needed to combat this escalating chronic disease crisis.

Area of Science:

  • Public Health
  • Epidemiology
  • Chronic Disease Management

Context:

  • Obesity is a critical global health challenge in the 21st century, escalating into an epidemic.
  • WHO projections indicated over 300 million people affected by 2005, with a trend of increasing prevalence.
  • The issue disproportionately affects children and adolescents, with significant percentages in developed nations and the Russian Federation experiencing overweight and obesity.

Purpose:

  • To highlight the escalating global epidemic of obesity.
  • To underscore the increasing prevalence of obesity across all age groups, including children and adolescents.
  • To emphasize the serious health consequences and societal impact of obesity.

Summary:

  • Obesity is a widespread chronic disease with epidemic proportions globally.
  • Prevalence is increasing, affecting younger populations and leading to significant health comorbidities.
  • Associated conditions include type 2 diabetes, hypertension, dyslipidemia, coronary heart disease, insulin resistance, and hyperinsulinemia.

Impact:

  • Obesity significantly contributes to early disability and reduced average life expectancy.
  • It is a major risk factor for numerous serious health conditions, including cardiovascular diseases and metabolic disorders.
  • Addressing obesity is crucial for improving public health outcomes and reducing healthcare burdens.

Keywords:
adipocytesapoptosischildrenobesity

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