Diabetic lung disease: fact or fiction?
Saeed Kolahian1,2,3, Veronika Leiss4, Bernd Nürnberg4,5
1Department of Pharmacology and Experimental Therapy, Institute of Experimental and Clinical Pharmacology and Toxicology, and Interfaculty Center of Pharmacogenomics and Drug Research (ICePhA), Eberhard Karls University Hospitals and Clinics, Tübingen, Germany. Saeed.Kolahian@med.uni-tuebingen.de.
Reviews in Endocrine & Metabolic Disorders
|October 23, 2019
Summary
Diabetes mellitus, a growing global health issue, is increasingly linked to lung diseases. This review explores how diabetes contributes to pulmonary fibrosis, a severe condition with few treatments.
Area of Science:
- Endocrinology and Pulmonology
- Metabolic and Respiratory Diseases
Background:
- Diabetes mellitus is a chronic metabolic disorder with rising global prevalence.
- Lung complications of diabetes are under-recognized but significant.
- Pulmonary fibrosis is a progressive lung disease with high mortality and limited treatment options.
Purpose of the Study:
- To review and discuss the role of diabetes mellitus in the progression of pulmonary diseases.
- To focus on the association between diabetes and pulmonary fibrosis.
Main Methods:
- Literature review and synthesis of existing studies.
- Analysis of the impact of diabetes on lung disease development.
Main Results:
- Emerging evidence suggests a connection between diabetes and increased risk/progression of lung disorders.
- Diabetes may exacerbate the pathogenesis of pulmonary fibrosis.
Conclusions:
- Diabetes mellitus plays a role in the progression of pulmonary diseases, particularly pulmonary fibrosis.
- Further research is needed to understand the mechanisms and develop targeted therapies.
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