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Updated: Jan 5, 2026

Preparation of Highly Porous Coordination Polymer Coatings on Macroporous Polymer Monoliths for Enhanced Enrichment of Phosphopeptides
Published on: July 14, 2015
[Preparation of metal-organic framework MIL-101(Cr) incorporated polymer monolithic column for on-line solid-phase
Chengxiong Yang1, Xueqing Yang1, Xiuping Yan2
1College of Chemistry, Research Center for Analytical Science, Nankai University, Tianjin 300071, China.
Abstract:
A metal-organic framework (MOF) MIL-101(Cr) incorporated polymer monolithic column was prepared, and a method was developed for the determination of 4-nitrophenol, 3-methylphenol, 2-nitrophenol and 2,4-dichlorophenol in water samples by on-line solid phase extraction (SPE) coupled with high performance liquid chromatography (HPLC). Effects of sample solution pH values, sample loading time, sample loading flow rates and desorption time on the on-line SPE of phenols were investigated. Under the optimized extraction conditions, large enhancement factors, wide linearity range, good precisions and low limits of detection were achieved. The results showed that the incorporation of MOFs in porous polymer monolith to fabricate MOF-incorporated monolith is one of the best ways to promote and expand the application of MOFs in on-line SPE.
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