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Pattern of Intermediate Uveitis in an Egyptian Cohort
Eiman Abd El Latif1, Ahmed Shawkat Abdelhalim2, Ahmed Samir Montasser3
1Department of Ophthalmology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Ocular Immunology and Inflammation
|October 24, 2019
Summary
Intermediate uveitis in Egypt often lacks a specific cause. When identified, sarcoidosis, tuberculosis, and multiple sclerosis are common underlying conditions requiring consideration.
Area of Science:
- Ophthalmology
- Immunology
- Systemic Inflammatory Diseases
Background:
- Intermediate uveitis is a form of intraocular inflammation.
- Identifying the underlying cause is crucial for effective management.
- Data on intermediate uveitis in Egypt is limited.
Purpose of the Study:
- To detail the clinical characteristics and etiological profile of intermediate uveitis.
- To analyze patient data from six tertiary eye centers in Egypt.
- To identify common causes and outcomes of intermediate uveitis in this population.
Main Methods:
- Multicenter retrospective chart review.
- Inclusion of 781 patients diagnosed with intermediate uveitis.
- Data collected between January 2010 and January 2017.
Main Results:
- Over half (58.77%) of cases were idiopathic.
- Identified causes included sarcoidosis (16.26%), tuberculosis (14.85%), and multiple sclerosis (9.09%).
- TINU accounted for 1.02% of cases; 62% of eyes achieved BCVA > 20/40.
Conclusions:
- A significant proportion of Egyptian intermediate uveitis patients have identifiable systemic causes.
- Sarcoidosis, tuberculosis, and multiple sclerosis are key differential diagnoses.
- Prompt recognition of these associated diseases is vital to prevent morbidity.
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