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Sensitive discrimination of glycoproteins and cell differentiation with an array sensing platform exploiting
Xin Lin1, Lifang Gao1, Jianhua Wang1
1Research Center for Analytical Sciences, Department of Chemistry, Northeastern University, Box 332, Shenyang 110819, China. chenxuwei@mail.neu.edu.cn.
Chemical Communications (Cambridge, England)
|October 25, 2019
Abstract:
An array sensing platform exploiting phenyl boronic acid-functionalized pyrene amphiphile/surfactant assemblies is constructed for glycoprotein discrimination, achieving a discrimination sensitivity of 50 nM. Gastric cancer cell lines of various differentiation grades are successfully discriminated, demonstrating its great potential in sensitive differentiation of glycoprotein-related samples in biomedical diagnosis.
