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    Area of Science:

    • Public Health
    • Epidemiology
    • Immunization Programs

    Background:

    • The Global Vaccine Action Plan (GVAP) aims for ≥90% national vaccine coverage by 2020.
    • Monitoring global vaccination trends is essential for public health initiatives.

    Purpose of the Study:

    • To present global, regional, and national vaccination coverage estimates and trends up to 2018.
    • To analyze vaccination dropout rates and coverage for various vaccines.

    Main Methods:

    • Utilized World Health Organization (WHO) and United Nations Children's Fund (UNICEF) global vaccination coverage estimates.
    • Analyzed data from 2010 to 2018, focusing on key vaccine doses and dropout rates.

    Main Results:

    • Global diphtheria, tetanus, and pertussis (DTP) coverage remained largely unchanged (DTP1: 90%, DTP3: 86% in 2018).
    • 19.4 million children were unvaccinated in 2018; 13.5 million received no DTP doses.
    • Measles-containing vaccine (MCV2) coverage increased significantly, but a 17% gap with MCV1 persisted.
    • Coverage for rotavirus, pneumococcal conjugate vaccine (PCV), rubella, Hib, and HepB vaccines increased.

    Conclusions:

    • Global vaccination coverage shows limited progress, highlighting persistent challenges in reaching immunization targets.
    • Tailored strategies are necessary to address local barriers and reach underserved populations for improved vaccination outcomes.