A Systematic Review of Pulp Revascularization Using a Triple Antibiotic Paste

Area of Science:

• Dentistry
• Regenerative Endodontics
• Pediatric Dentistry

Background:

• Pulp revascularization is a regenerative treatment for immature teeth with necrotic pulp.
• Triple antibiotic paste has been investigated for its efficacy in this procedure.

Purpose of the Study:

• To systematically review clinical and radiographic outcomes of pulp revascularization using triple antibiotic paste in immature teeth.
• To evaluate the effectiveness of this regenerative approach.

Main Methods:

• Comprehensive electronic literature searches were performed across multiple databases.
• Eight clinical trials were included for qualitative analysis after screening 1,768 references.
• Study quality was assessed using the Cochrane Collaboration tool.

Main Results:

• Included studies showed clinical and radiographic success in pulp revascularization.
• Triple antibiotic paste demonstrated effectiveness in resolving symptoms and achieving periapical healing.
• The risk of bias in the included studies varied from low to unclear.

Conclusions:

• Triple antibiotic paste is an effective option for pulp revascularization in immature teeth.
• The treatment leads to absence of symptoms and restoration of periapical integrity.
• Further research may be needed to clarify the risk of bias in existing studies.