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Related Experiment Video

Updated: Jan 5, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

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Microvascular Changes Associated with Optic Disc Drusen: Case Report

Özlem Biçer¹, Huban Atilla¹

¹Ankara University Faculty of Medicine, Department of Ophthalmology, Ankara, Turkey

Turkish Journal of Ophthalmology

|October 26, 2019

Summary

Optic disc drusen (ODD) can mimic papilledema. Multimodal imaging, including OCTA, revealed ODD structural changes and capillary dropout, aiding accurate diagnosis.

Keywords:

Optic disc drusen optical coherence tomography angiography imaging modalities pseudopapilledema microvascular changes

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Area of Science:

Ophthalmology
Medical Imaging

Background:

Optic disc drusen (ODD) are often misdiagnosed as papilledema due to similar optic disc appearance.
Early and accurate diagnosis of ODD is crucial for appropriate patient management.

Observation:

A 17-year-old male presented with headaches and bilateral blurred optic disc margins.
Multimodal imaging, including B-scan ultrasonography, FAF, OCT, OCTA, and visual field testing, was performed.

Findings:

Bilateral ODD was confirmed via B-scan USG.
FAF showed optic disc hyperautofluorescence.
OCT revealed elevated disc borders and RNFL thinning.
Visual field testing detected nasal field loss.
OCTA demonstrated capillary dropout and reduced vessel density in the peripapillary and macular areas.

Implications:

Multimodal imaging, particularly OCTA, provides detailed structural and vascular insights into ODD.
This case highlights the utility of advanced imaging in differentiating ODD from papilledema.
Understanding ODD's vascular changes is key for comprehensive ophthalmological assessment.