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Ralstonia mannitolilytica sepsis: a case report
Michael Owusu1,2, Godfred Acheampong2, Augustina Annan2,3
1Department of Medical Diagnostics, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Ralstonia mannitolilytica, an emerging pathogen, caused sepsis in a Ghanaian child. This case highlights the need for better diagnostics and antibiotic stewardship in Africa.
Area of Science:
- Medical Microbiology
- Infectious Diseases
Background:
- Ralstonia mannitolilytica is an emerging opportunistic pathogen.
- It is associated with severe diseases like septic shock and meningitis.
- Limited reports exist, particularly from Africa.
Observation:
- A 2-year-old child in Ghana presented with fever and chills.
- Ralstonia mannitolilytica was identified in blood cultures using conventional and 16S ribosomal DNA methods.
- The patient showed clinical improvement after cefuroxime treatment.
Findings:
- This case confirms R. mannitolilytica as a cause of sepsis.
- Successful treatment with cefuroxime was observed.
- Highlights the pathogen's presence in an underreported region.
Implications:
- Emphasizes the need for enhanced laboratory diagnostics for R. mannitolilytica in Africa.
- Stresses the importance of evidence-based antibiotic selection over presumptive treatment.
- Underscores the potential for severe infections in vulnerable populations in rural settings.
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