Related Experiment Video
Updated: Jan 4, 2026
An In Vitro Model of a Parallel-Plate Perfusion System to Study Bacterial Adherence to Graft Tissues
Published on: January 7, 2019
Impact of Setting up an "Endocarditis Team" on the Management of Infective Endocarditis
Yvon Ruch1, Jean-Philippe Mazzucotelli2, François Lefebvre3
1Department of Infectious Disease, Strasbourg University Hospital, Strasbourg, France.
Insights
Establishing an Endocarditis Team (ET) improved patient survival and reduced treatment times for infective endocarditis (IE). This multidisciplinary approach is crucial for managing this severe heart infection effectively.
Area of Science:
- Cardiology
- Infectious Diseases
- Healthcare Management
Background:
- Infective endocarditis (IE) is a serious condition with high mortality rates.
- Multidisciplinary teams, or Endocarditis Teams (ET), are recommended for managing IE in specialized centers.
Purpose of the Study:
- To evaluate the impact of an Endocarditis Team (ET) on patient outcomes.
- To assess the effect of the ET on mortality, treatment duration, and hospital stay.
Main Methods:
- A monocentric observational study was conducted at Strasbourg University Hospital from 2012 to 2017.
- In-hospital mortality was the primary endpoint; secondary endpoints included mortality, surgery rates, treatment times, and length of stay.
- Predictors of in-hospital mortality were analyzed.
Main Results:
- The study analyzed 391 IE episodes.
- The post-ET period showed a significant reduction in time to surgery, duration of antibiotic therapy, and length of hospital stay.
- Multivariate analysis indicated the post-ET period was positively associated with survival (OR, 0.45; P = .048).
Conclusions:
- A multidisciplinary approach, specifically the Endocarditis Team (ET), positively impacts IE management.
- Implementing ETs should be considered in all hospitals treating infective endocarditis.
Background:
Infective endocarditis (IE) remains a severe disease with a high mortality rate. Therefore, guidelines encourage the setup of a multidisciplinary group in reference centers. The present study evaluated the impact of this "Endocarditis Team" (ET).
Methods:
We conducted a monocentric observational study at Strasbourg University Hospital, Strasbourg, France, between 2012 and 2017. The primary end point was in-hospital mortality. Secondary end points were 6-month and 1-year mortality, surgery rate, time to surgical procedure, duration of effective antibiotic therapy, length of in-hospital stay, and sequelae. We also assessed predictors of in-hospital mortality.
Results:
We analyzed 391 episodes of IE. In the post-ET period, there was a nonsignificant decrease in in-hospital mortality (20.3% vs 14.7%, respectively; P = .27) and sequelae, along with a significant reduction in time to surgery (16.4 vs 10.3 days, respectively; P = .049), duration of antibiotic therapy (55.2 vs 47.2 days, respectively; P < .001), and length of in-hospital stay (40.6 vs 31.9 days, respectively; P < .01). In a multivariate analysis, the post-ET period was positively associated with survival (odds ratio, 0.45; 95% confidence interval, 0.20-0.96; P = .048).
Conclusions:
This multidisciplinary approach exerted a positive impact on the management of IE and should be considered in all hospitals managing IE.
More Related Videos
Related Concept Videos
01:18Endocarditis III: Medical Management
01:29Endocarditis IV: Nursing Management
01:25Endocarditis I: Introduction
01:25Endocarditis II: Clinical Features of Infective Endocarditis
01:14Myocarditis III: Medical Management
01:22Myocarditis IV: Nursing Management